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Ortho Molecular Adren-All, 120 Capsules beauty Clear clinical support for aStress is defined as any disturbanceextreme cold or heat, psychological stress, sleep deprivation, work overload, physical trauma, as well as toxic exposure, that can trigger the stress response. The bodys stress response system is comprised of the hypothalamic pituitary adrenal (HPA) axis. Prolonged stress triggers the HPA axis and consists of three stages: stage 1: alarm; stage 2: resistance; and stage 3: exhaustion. The initial, short lived phase